Obesity and epithelial ovarian cancer survival: a systematic review and meta-analysis.

ABSTRACT:

Background

Studies on the association between obesity and ovarian cancer survival have had conflicting results. We reviewed and quantitatively summarized the existing evidence, exploring potentially important sources of variability, such as the timing of body mass index (BMI) assessment, BMI cut points, references used in multivariate analysis, and ovarian cancer stage.

Methods

Eligible studies were searched using MEDLINE (PubMed), EMBASE, and Cochrane Central Register of Controlled Trials, relevant bibliographies were manually reviewed for additional studies. Adjusted hazard ratios (HRs) from individual studies were pooled using a random effects model.

Results

17 cohort studies of 929 screened articles were included in the final analysis. Obesity in early adulthood a

SUBMITTER: Bae HS 

PROVIDER: S-EPMC4022349 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature