Structurally-constrained relationships between cognitive states in the human brain.

ABSTRACT: The anatomical connectivity of the human brain supports diverse patterns of correlated neural activity that are thought to underlie cognitive function. In a manner sensitive to underlying structural brain architecture, we examine the extent to which such patterns of correlated activity systematically vary across cognitive states. Anatomical white matter connectivity is compared with functional correlations in neural activity measured via blood oxygen level dependent (BOLD) signals. Functional connectivity is separately measured at rest, during an attention task, and during a memory task. We assess these structural and functional measures within previously-identified resting-state functional networks, denoted task-positive and task-negative networks, that have been independently shown to be

SUBMITTER: Hermundstad AM 

PROVIDER: S-EPMC4022461 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature