Diabetes mellitus and poorer prognosis in hepatocellular carcinoma: a systematic review and meta-analysis.

ABSTRACT:

Background

Previous studies suggested that diabetes mellitus was associated with cancer risk and prognosis, but studies investigating the relationship between diabetes mellitus and survival in patients with hepatocellular carcinoma (HCC) reported inconsistent findings. To derive a more precise estimate of the prognostic role of diabetes mellitus in HCC, we systematically reviewed published studies and carried out a meta-analysis.

Methods

Eligible articles were identified in electronic databases from their inception through September 16, 2013. To evaluate the correlation between diabetes mellitus and prognosis in HCC, the pooled hazard ratios (HR) and their 95% confidence intervals (95% CI) for poorer overall and disease-free survivals were calculated by standard meta-analysi

SUBMITTER: Wang YG 

PROVIDER: S-EPMC4022589 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature