Preventing the onset of major depressive disorder: a meta-analytic review of psychological interventions.

ABSTRACT:

Background

Depressive disorders are highly prevalent, have a detrimental impact on the quality of life of patients and their relatives and are associated with increased mortality rates, high levels of service use and substantial economic costs. Current treatments are estimated to only reduce about one-third of the disease burden of depressive disorders. Prevention may be an alternative strategy to further reduce the disease burden of depression.

Methods

We conducted a meta-analysis of randomized controlled trials examining the effects of preventive interventions in participants with no diagnosed depression at baseline on the incidence of diagnosed depressive disorders at follow-up. We identified 32 studies that met our inclusion criteria.

Results

We found that the rel

SUBMITTER: van Zoonen K 

PROVIDER: S-EPMC4023317 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature