Association between serotonin transport polymorphisms and postdischarge nausea and vomiting in women following breast cancer surgery.

ABSTRACT:

Purpose/objectives

To examine the association of the serotonin transport gene and postdischarge nausea and vomiting (PDNV) in women following breast cancer surgery.

Design

A cross-sectional study.

Setting

A comprehensive cancer center in Pittsburgh, PA.

Sample

80 post-menopausal women treated surgically for early-stage breast cancer.

Methods

Data were collected using standardized instruments after surgery but before the initiation of chemotherapy. Blood or saliva were used for DNA extraction and analyzed following standardized protocols. Data were analyzed using descriptive statistics and logistic regression.

Main research variables

Serotonin transport gene (SLC6A4), nausea, vomiting, pain, and anxiety.

Findings

Women who inherited the LA/L

SUBMITTER: Wesmiller SW 

PROVIDER: S-EPMC4023462 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature