Positive correlation between the expression of hEag1 and HIF-1α in breast cancers: an observational study.

ABSTRACT:

Objectives

To explore the expression patterns of Eag1 (ether á go-go 1) and HIF-1α (hypoxia-inducible factor 1α) in a cohort of patients with breast cancer.

Setting

Department of general surgery in an upper first-class hospital in Xi'an, China.

Participants

A total of 112 female Han Chinese patients with a diagnosis of invasive ductal carcinoma were included. Patients with main internal diseases, such as cardiovascular, endocrine, gastroenterological, haematological, infectious diseases, etc, were excluded.

Primary and secondary outcome measures

Expression profiles of Eag1 and HIF-1α.

Results

Eag1 and HIF-1α were overexpressed in the tumour tissues compared with the pair-matched control tissues, p=0.002 and <0.001, respectively. The expression of Eag1 an

SUBMITTER: Lai Q 

PROVIDER: S-EPMC4025446 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature