Final results from the Betaseron (interferon β-1b) Pregnancy Registry: a prospective observational study of birth defects and pregnancy-related adverse events.

ABSTRACT:

Objective

Women with multiple sclerosis are often diagnosed and treated during their reproductive years. Limited data are available on the safety of treatment during pregnancy. The Betaseron Pregnancy Registry prospectively monitored women exposed to interferon β-1b (IFNβ-1b) during pregnancy to estimate the rates of birth defects, spontaneous abortions (SABs) and other negative outcomes in this population.

Design

From 2006 to 2011, this observational registry enrolled women exposed prior to conception or during pregnancy (but prior to or without abnormalities on prenatal screening). Follow-up continued from enrolment through the 4-month paediatric visit.

Setting

Patients in the USA who met these criteria were enrolled in the registry.

Results

The registry enro

SUBMITTER: Coyle PK 

PROVIDER: S-EPMC4025462 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature