Yeast growth plasticity is regulated by environment-specific multi-QTL interactions.

ABSTRACT: For a unicellular, nonmotile organism like Saccharomyces cerevisiae, carbon sources act as nutrients and as signaling molecules; consequently, these sources affect various fitness parameters, including growth. It is therefore advantageous for yeast strains to adapt their growth to carbon source variation. The ability of a given genotype to manifest different phenotypes in varying environments is known as phenotypic plasticity. To identify quantitative trait loci (QTL) that drive plasticity in growth, two growth parameters (growth rate and biomass) were measured for a set of meiotic recombinants of two genetically divergent yeast strains grown in different carbon sources. To identify QTL contributing to plasticity across pairs of environments, gene-environment interaction mapping was perfor

SUBMITTER: Bhatia A 

PROVIDER: S-EPMC4025475 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature