Spontaneous regression of metastatic cancer cells in the lymph node: a case report.

ABSTRACT:

Background

Spontaneous regression of a malignant tumor is the phenomenon of disappearance of cancer cells without any treatments and it can be induced by an enhanced tumor-targeting immune response. However, there has not been a comprehensive immunological overview to compare the tumor-regressed lymph nodes and metastatic lymph nodes in the same patient.

Case presentation

We conducted a histologic analysis of various immune cells in an Asian female patient with buccal cancer (squamous cell carcinomas), in which the spontaneous regression of metastatic lymphadenopathy was confirmed by surgical pathology. The immune cell profiles between the metastatic nodes and the tumor-regressed nodes were compared. Tumor regression was confirmed by hematoxylin & eosin and cytokeratin/Ki-67

SUBMITTER: Choi N 

PROVIDER: S-EPMC4025537 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature