Original Design of Fluorescent Ligands by Fusing BODIPY and Melatonin Neurohormone.

ABSTRACT: An original design and synthesis of fluorescent ligands for melatonin receptor studies is presented and consists in the fusion of the endogenous ligand with the fluorescent BODIPY core. Probes I-IV show high affinities for MT1 and MT2 melatonin receptors and exhibit fluorescence properties compatible with cell observation.

SUBMITTER: Thireau J 

PROVIDER: S-EPMC4027590 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature