Helicobacter pylori eradication therapy to prevent gastric cancer in healthy asymptomatic infected individuals: systematic review and meta-analysis of randomised controlled trials.

ABSTRACT:

Objectives

To determine whether searching for Helicobacter pylori and treating with eradication therapy leads to a reduction in incidence of gastric cancer among healthy asymptomatic infected individuals.

Design

Systematic review and meta-analysis of randomised controlled trials.

Data sources

Medline, Embase, and the Cochrane central register of controlled trials were searched through to December 2013. Conference proceedings between 2001 and 2013 were hand searched. A recursive search was performed with bibliographies of relevant studies. There were no language restrictions.

Eligibility criteria for selecting studies

Randomised controlled trials examining the effect of at least seven days of eradication therapy on subsequent occurrence of gastric cancer in adul

SUBMITTER: Ford AC 

PROVIDER: S-EPMC4027797 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature