Recovery of echocardiographic function in children with idiopathic dilated cardiomyopathy: results from the pediatric cardiomyopathy registry.

ABSTRACT:

Objectives

This study sought to determine the incidence and predictors of recovery of normal echocardiographic function among children with idiopathic dilated cardiomyopathy (DCM).

Background

Most children with idiopathic DCM have poor outcomes; however, some improve.

Methods

We studied children <18 years of age from the Pediatric Cardiomyopathy Registry who had both depressed left ventricular (LV) function (fractional shortening or ejection fraction z-score <-2) and LV dilation (end-diastolic dimension [LVEDD] z-score >2) at diagnosis and who had at least 1 follow-up echocardiogram 30 days to 2 years from the initial echocardiogram. We estimated the cumulative incidence and predictors of normalization.

Results

Among 868 children who met the inclusion criteria,

SUBMITTER: Everitt MD 

PROVIDER: S-EPMC4030008 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature