Monotonous diets protect against acute colitis in mice: epidemiologic and therapeutic implications.

ABSTRACT:

Objectives

Multiple characteristics of industrialization have been proposed to contribute to the global emergence of inflammatory bowel diseases (IBDs: Crohn disease and ulcerative colitis). Major changes in eating habits during the last decades and the effectiveness of exclusive enteral nutrition in the treatment of Crohn disease indicate the etiologic importance of dietary intake in IBDs. A uniform characteristic of nutrition in developing countries (where the incidence of IBD is low) and exclusive enteral nutrition is their consistent nature for prolonged periods; however, the potentially beneficial effect of dietary monotony in respect to mammalian intestinal inflammation has not been examined.

Methods

The association between alternating (2 different complete chows) and

SUBMITTER: Nagy-Szakal D 

PROVIDER: S-EPMC4030530 | biostudies-literature | 2013 May

REPOSITORIES: biostudies-literature