Effects of early blood pressure lowering on early and long-term outcomes after acute stroke: an updated meta-analysis.

ABSTRACT:

Background

Hypertension is common after acute stroke onset. Previous studies showed controversial effects of early blood pressure (BP) lowering on stroke outcomes. The aim of this study is to assess the effects of early BP lowering on early and long-term outcomes after acute stroke.

Methods

A meta-analysis was conducted with prospective randomized controlled trials assessing the effects of early BP lowering on early and long-term outcomes after acute stroke compared with placebo. Literature searching was performed in the databases from inception to December 2013. New evidence from recent trials were included. Outcomes were analyzed as early (within 30 days) and long-term (from 3 to 12 months) endpoints using summary estimates of relative risks (RR) and their 95% confidence i

SUBMITTER: Wang H 

PROVIDER: S-EPMC4031127 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature