Voluntary activation of the sympathetic nervous system and attenuation of the innate immune response in humans.

ABSTRACT: Excessive or persistent proinflammatory cytokine production plays a central role in autoimmune diseases. Acute activation of the sympathetic nervous system attenuates the innate immune response. However, both the autonomic nervous system and innate immune system are regarded as systems that cannot be voluntarily influenced. Herein, we evaluated the effects of a training program on the autonomic nervous system and innate immune response. Healthy volunteers were randomized to either the intervention (n = 12) or control group (n = 12). Subjects in the intervention group were trained for 10 d in meditation (third eye meditation), breathing techniques (i.a., cyclic hyperventilation followed by breath retention), and exposure to cold (i.a., immersions in ice cold water). The control group was no

SUBMITTER: Kox M 

PROVIDER: S-EPMC4034215 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature