Vitamin D intake, blood 25(OH)D levels, and breast cancer risk or mortality: a meta-analysis.

ABSTRACT:

Background

Experimental studies suggest potential anti-carcinogenic properties of vitamin D against breast cancer risk, but the epidemiological evidence to date is inconsistent.

Methods

We searched MEDLINE and EMBASE databases along with a hand search for eligible studies to examine the association between vitamin D status (based on diet and blood 25-hydroxyvitamin D (25(OH)D)) and breast cancer risk or mortality in a meta-analysis. A random-effect model was used to calculate a pooled adjusted relative risk (RR).

Results

A total of 30 prospective studies (nested case-control or cohort) were included for breast cancer incidence (n=24 studies; 31 867 cases) or mortality (n=6 studies; 870 deaths) among 6092 breast cancer patients. The pooled RRs of breast cancer incidenc

SUBMITTER: Kim Y 

PROVIDER: S-EPMC4037823 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature