LincSNP: a database of linking disease-associated SNPs to human large intergenic non-coding RNAs.

ABSTRACT:

Background

Genome-wide association studies (GWAS) have successfully identified a large number of single nucleotide polymorphisms (SNPs) that are associated with a wide range of human diseases. However, many of these disease-associated SNPs are located in non-coding regions and have remained largely unexplained. Recent findings indicate that disease-associated SNPs in human large intergenic non-coding RNA (lincRNA) may lead to susceptibility to diseases through their effects on lincRNA expression. There is, therefore, a need to specifically record these SNPs and annotate them as potential candidates for disease.

Description

We have built LincSNP, an integrated database, to identify and annotate disease-associated SNPs in human lincRNAs. The current release of LincSNP contains

SUBMITTER: Ning S 

PROVIDER: S-EPMC4038069 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature