Interventions to improve delivery of isoniazid preventive therapy: an overview of systematic reviews.

ABSTRACT:

Background

Uptake of isoniazid preventive therapy (IPT) to prevent tuberculosis has been poor, particularly in the highest risk populations. Interventions to improve IPT delivery could promote implementation. The large number of existing systematic reviews on treatment adherence has made drawing conclusions a challenge. To provide decision makers with the evidence they need, we performed an overview of systematic reviews to compare different organizational interventions to improve IPT delivery as measured by treatment completion among those at highest risk for the development of TB disease, namely child contacts or HIV-infected individuals.

Methods

We searched the Cochrane Database of Systematic Reviews, the Database of Abstracts of Reviews of Effects (DARE), and MEDLINE up

SUBMITTER: Adams LV 

PROVIDER: S-EPMC4038070 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature