Genome-wide association studies of refractive error and myopia, lessons learned, and implications for the future.

ABSTRACT: The investigation of the genetic basis of refractive error and myopia entered a new stage with the introduction of genome-wide association studies (GWAS). Multiple GWAS on many ethnic groups have been published over the years, providing new insight into the genetic architecture and pathophysiology of refractive error. This is a review of the GWAS published to date, the main lessons learned, and future possible directions of genetic studies of myopia and refractive error.

SUBMITTER: Hysi PG 

PROVIDER: S-EPMC4039381 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature