The relationship between the nicotine metabolite ratio and three self-report measures of nicotine dependence across sex and race.

ABSTRACT:

Rationale

Variability in the rate of nicotine metabolism, measured by the nicotine metabolite ratio (NMR), is associated with smoking behavior. However, data linking the NMR with nicotine dependence measured by the Fagerström test for nicotine dependence (FTND) are mixed. Few past studies have examined alternative measures of nicotine dependence and how this relationship may vary by sex and race.

Objective

Using data from smokers undergoing eligibility evaluation for a smoking cessation clinical trial (n = 833), this study examined variability in the relationship between NMR and nicotine dependence across sex and race and using three measures of nicotine dependence: FTND, time-to-first-cigarette (TTFC), and the heaviness of smoking index (HSI).

Results

Controlling for

SUBMITTER: Schnoll RA 

PROVIDER: S-EPMC4040302 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature