Evaluating the optimal timing of surgical antimicrobial prophylaxis: study protocol for a randomized controlled trial.

ABSTRACT:

Background

Surgical site infections are the most common hospital-acquired infections among surgical patients. The administration of surgical antimicrobial prophylaxis reduces the risk of surgical site infections . The optimal timing of this procedure is still a matter of debate. While most studies suggest that it should be given as close to the incision time as possible, others conclude that this may be too late for optimal prevention of surgical site infections. A large observational study suggests that surgical antimicrobial prophylaxis should be administered 74 to 30 minutes before surgery. The aim of this article is to report the design and protocol of a randomized controlled trial investigating the optimal timing of surgical antimicrobial prophylaxis.

Methods/design

In

SUBMITTER: Mujagic E 

PROVIDER: S-EPMC4040488 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature