Screening of Lactobacillus spp. for the prevention of Pseudomonas aeruginosa pulmonary infections.

ABSTRACT:

Background

Pseudomonas aeruginosa is an opportunistic pathogen that significantly increases morbidity and mortality in nosocomial infections and cystic fibrosis patients. Its pathogenicity especially relies on the production of virulence factors or resistances to many antibiotics. Since multiplication of antibiotic resistance can lead to therapeutic impasses, it becomes necessary to develop new tools for fighting P. aeruginosa infections. The use of probiotics is one of the ways currently being explored. Probiotics are microorganisms that exert a positive effect on the host's health and some of them are known to possess antibacterial activities. Since most of their effects have been shown in the digestive tract, experimental data compatible with the respiratory environment are stro

SUBMITTER: Alexandre Y 

PROVIDER: S-EPMC4040502 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature