Processes to manage analyses and publications in a phase III multicenter randomized clinical trial.

ABSTRACT:

Background

The timely publication of findings in peer-reviewed journals is a primary goal of clinical research. In clinical trials, the processes leading to publication can be complex from choice and prioritization of analytic topics through to journal submission and revisions. As little literature exists on the publication process for multicenter trials, we describe the development, implementation, and effectiveness of such a process in a multicenter trial.

Methods

The Hepatitis C Antiviral Long-Term Treatment against Cirrhosis (HALT-C) trial included a data coordinating center (DCC) and clinical centers that recruited and followed more than 1,000 patients. Publication guidelines were approved by the steering committee, and the publications committee monitored the publicati

SUBMITTER: Snow KK 

PROVIDER: S-EPMC4040510 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature