Fate and uptake of pharmaceuticals in soil-earthworm systems.

ABSTRACT: Pharmaceuticals present a potential threat to soil organisms, yet our understanding of their fate and uptake in soil systems is limited. This study therefore investigated the fate and uptake of (14)C-labeled carbamazepine, diclofenac, fluoxetine, and orlistat in soil-earthworm systems. Sorption coefficients increased in the order of carbamazepine < diclofenac < fluoxetine < orlistat. Dissipation of (14)C varied by compound, and for orlistat, there was evidence of formation of nonextractable residues. Uptake of (14)C was seen for all compounds. Depuration studies showed complete elimination of (14)C for carbamazepine and fluoxetine treatments and partial elimination for orlistat and diclofenac, with greater than 30% of the (14)C remaining in the tissue at the end of the experiment. Pore-wat

SUBMITTER: Carter LJ 

PROVIDER: S-EPMC4041664 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature