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The H2A/H2B-like histone-fold domain proteins at the crossroad between chromatin and different DNA metabolisms.


ABSTRACT: Core histones are the building block of chromatin and among the most highly conserved proteins in eukaryotes. The related "deviant" histones share the histone-fold domain, and serve various roles in DNA metabolism. We provide here a structural and functional outlook of H2A/H2B-like deviant histones in transcription, replication and remodeling.

SUBMITTER: Gnesutta N 

PROVIDER: S-EPMC4042584 | biostudies-literature | 2013 May-Jun

REPOSITORIES: biostudies-literature

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The H2A/H2B-like histone-fold domain proteins at the crossroad between chromatin and different DNA metabolisms.

Gnesutta Nerina N   Nardini Marco M   Mantovani Roberto R  

Transcription 20130516 3


Core histones are the building block of chromatin and among the most highly conserved proteins in eukaryotes. The related "deviant" histones share the histone-fold domain, and serve various roles in DNA metabolism. We provide here a structural and functional outlook of H2A/H2B-like deviant histones in transcription, replication and remodeling. ...[more]

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