The H2A/H2B-like histone-fold domain proteins at the crossroad between chromatin and different DNA metabolisms.

ABSTRACT: Core histones are the building block of chromatin and among the most highly conserved proteins in eukaryotes. The related "deviant" histones share the histone-fold domain, and serve various roles in DNA metabolism. We provide here a structural and functional outlook of H2A/H2B-like deviant histones in transcription, replication and remodeling.

SUBMITTER: Gnesutta N 

PROVIDER: S-EPMC4042584 | biostudies-literature | 2013 May-Jun

REPOSITORIES: biostudies-literature