A network meta-analysis of the relative efficacy of treatments for actinic keratosis of the face or scalp in Europe.

ABSTRACT:

Background

Several treatments are available for actinic keratosis (AK) on the face and scalp. Most treatment modalities were compared to placebo and therefore little is known on their relative efficacy.

Objectives

To compare the different treatments for mild to moderate AK on the face and scalp available in clinical practice in Europe.

Methods

A network meta-analysis (NMA) was performed on the outcome "complete patient clearance". Ten treatment modalities were included: two 5-aminolaevulinic acid photodynamic therapies (ALA-PDT), applied as gel (BF-200 ALA) or patch; methyl-aminolevulinate photodynamic therapy (MAL-PDT); three modalities with imiquimod (IMI), applied as a 4-week or 16-week course with 5% imiquimod, or a 2-3 week course with 3.75% imiquimod; cryotherap

SUBMITTER: Vegter S 

PROVIDER: S-EPMC4043670 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature