Overexpression of UCP1 in tobacco induces mitochondrial biogenesis and amplifies a broad stress response.

ABSTRACT:

Background

Uncoupling protein one (UCP1) is a mitochondrial inner membrane protein capable of uncoupling the electrochemical gradient from adenosine-5'-triphosphate (ATP) synthesis, dissipating energy as heat. UCP1 plays a central role in nonshivering thermogenesis in the brown adipose tissue (BAT) of hibernating animals and small rodents. A UCP1 ortholog also occurs in plants, and aside from its role in uncoupling respiration from ATP synthesis, thereby wasting energy, it plays a beneficial role in the plant response to several abiotic stresses, possibly by decreasing the production of reactive oxygen species (ROS) and regulating cellular redox homeostasis. However, the molecular mechanisms by which UCP1 is associated with stress tolerance remain unknown.

Results

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SUBMITTER: Barreto P 

PROVIDER: S-EPMC4046140 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature