QUALITY OF LIFE/AFTERCARE

ABSTRACT: INTRODUCTION: Obesity is a long-term morbidity for children diagnosed with CNS tumors. BMI normally declines until the age of adiposity rebound (AR), after which it increases. Tumor location, radiation therapy, or surgery near the hypothalamus increases the risk of obesity. We hypothesized involvement of the hypothalamus would result in a greater BMI, and diagnosis/treatment before AR would lead to the greatest BMI. STUDY METHODS: Retrospective cohort of brain tumor survivors diagnosed from 2001-2011 at Children's Hospital of Wisconsin: chart review extracted BMI z score at diagnosis and two-year follow-up. Children were categorized into six groups, based on age at diagnosis and hypothalamic involvement (HI). Consistent with CDC growth curves, ages were classified as "before AR" (0-41.99 m

SUBMITTER: Strobel K 

PROVIDER: S-EPMC4046295 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature