Amygdala activation during emotional face processing in adolescents with affective disorders: the role of underlying depression and anxiety symptoms.

ABSTRACT: Depressive and anxiety disorders are often first diagnosed during adolescence and it is known that they persist into adulthood. Previous studies often tried to dissociate depressive and anxiety disorders, but high comorbidity makes this difficult and maybe even impossible. The goal of this study was to use neuroimaging to test what the unique contribution is of depression and anxiety symptomatology on emotional processing and amygdala activation, and to compare the results with a healthy control group. We included 25 adolescents with depressive and/or anxiety disorders and 26 healthy adolescents. Participants performed an emotional face processing task while in the MRI scanner. We were particularly interested in the relation between depression/anxiety symptomatology and patterns of amygdal

SUBMITTER: van den Bulk BG 

PROVIDER: S-EPMC4046490 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature