CEG: a database of essential gene clusters.

ABSTRACT:

Background

Essential genes are indispensable for the survival of living entities. They are the cornerstones of synthetic biology, and are potential candidate targets for antimicrobial and vaccine design.

Description

Here we describe the Cluster of Essential Genes (CEG) database, which contains clusters of orthologous essential genes. Based on the size of a cluster, users can easily decide whether an essential gene is conserved in multiple bacterial species or is species-specific. It contains the similarity value of every essential gene cluster against human proteins or genes. The CEG_Match tool is based on the CEG database, and was developed for prediction of essential genes according to function. The database is available at http://cefg.uestc.edu.cn/ceg.

Conclusions

SUBMITTER: Ye YN 

PROVIDER: S-EPMC4046693 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature