A two-locus model of spatially varying stabilizing or directional selection on a quantitative trait.

ABSTRACT: The consequences of spatially varying, stabilizing or directional selection on a quantitative trait in a subdivided population are studied. A deterministic two-locus two-deme model is employed to explore the effects of migration, the degree of divergent selection, and the genetic architecture, i.e., the recombination rate and ratio of locus effects, on the maintenance of genetic variation. The possible equilibrium configurations are determined as functions of the migration rate. They depend crucially on the strength of divergent selection and the genetic architecture. The maximum migration rates are investigated below which a stable fully polymorphic equilibrium or a stable single-locus polymorphism can exist. Under stabilizing selection, but with different optima in the demes, strong reco

SUBMITTER: Geroldinger L 

PROVIDER: S-EPMC4048038 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature