Risk prediction scores for recurrence and progression of non-muscle invasive bladder cancer: an international validation in primary tumours.

ABSTRACT:

Objective

We aimed to determine the validity of two risk scores for patients with non-muscle invasive bladder cancer in different European settings, in patients with primary tumours.

Methods

We included 1,892 patients with primary stage Ta or T1 non-muscle invasive bladder cancer who underwent a transurethral resection in Spain (n = 973), the Netherlands (n = 639), or Denmark (n = 280). We evaluated recurrence-free survival and progression-free survival according to the European Organisation for Research and Treatment of Cancer (EORTC) and the Spanish Urological Club for Oncological Treatment (CUETO) risk scores for each patient and used the concordance index (c-index) to indicate discriminative ability.

Results

The 3 cohorts were comparable according to age and sex,

SUBMITTER: Vedder MM 

PROVIDER: S-EPMC4048166 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature