Prescribing pattern of anti-Parkinson drugs in Japan: a trend analysis from 2005 to 2010.

ABSTRACT:

Objective

Therapeutic options for Parkinson's disease mainly consist of L-dopa and dopamine agonists. However, in Japan, the product labeling of the ergot dopamine agonists, cabergoline and pergolide, was revised in April 2007 due to the risk of developing cardiac valvulopathy. Here, we describe the prescribing trends of anti-Parkinson drugs from 2005 through 2010 in Japan, and examined whether these trends changed after the drug safety measures in 2007.

Methods and patients

We used medical claim data from January 2005 to December 2010 for Parkinson's disease patients older than 30 years who were prescribed anti-Parkinson drugs. We calculated the proportion of patients prescribed each drug for each year, and compared the proportions of first-line drugs prescribed before and

SUBMITTER: Nakaoka S 

PROVIDER: S-EPMC4048287 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature