A Genomic Approach for Distinguishing between Recent and Ancient Admixture as Applied to Cattle.

ABSTRACT: Genomic data facilitate opportunities to track complex population histories of divergence and gene flow. We developed a metric, scaled block size (SBS), which uses the nonrecombined block size of introgressed regions of chromosomes to differentiate between recent and ancient types of admixture, and applied it to the reconstruction of admixture in cattle. Cattle are descendants of 2 independently domesticated lineages, taurine and indicine, which diverged more than 200 000 years ago. Several breeds have hybrid ancestry between these divergent lineages. Using 47 506 single-nucleotide polymorphisms, we analyzed the genomic architecture of the ancestry of 1369 individuals. We focused on 4 groups with admixed ancestry, including 2 anciently admixed African breeds (n = 58; n = 43), New World cat

SUBMITTER: McTavish EJ 

PROVIDER: S-EPMC4048551 | biostudies-literature | 2014 Jul-Aug

REPOSITORIES: biostudies-literature