Graph theoretical analysis of resting-state MEG data: Identifying interhemispheric connectivity and the default mode.

ABSTRACT: Interhemispheric connectivity with resting state MEG has been elusive, and demonstration of the default mode network (DMN) yet more challenging. Recent seed-based MEG analyses have shown interhemispheric connectivity using power envelope correlations. The purpose of this study is to compare graph theoretic maps of brain connectivity generated using MEG with and without signal leakage correction to evaluate for the presence of interhemispheric connectivity. Eight minutes of resting state eyes-open MEG data were obtained in 22 normal male subjects enrolled in an IRB-approved study (ages 16-18). Data were processed using an in-house automated MEG processing pipeline and projected into standard (MNI) source space at 7mm resolution using a scalar beamformer. Mean beta-band amplitude was sampled

SUBMITTER: Maldjian JA 

PROVIDER: S-EPMC4049007 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature