Liver stiffness value-based risk estimation of late recurrence after curative resection of hepatocellular carcinoma: development and validation of a predictive model.

ABSTRACT:

Background

Preoperative liver stiffness (LS) measurement using transient elastography (TE) is useful for predicting late recurrence after curative resection of hepatocellular carcinoma (HCC). We developed and validated a novel LS value-based predictive model for late recurrence of HCC.

Methods

Patients who were due to undergo curative resection of HCC between August 2006 and January 2010 were prospectively enrolled and TE was performed prior to operations by study protocol. The predictive model of late recurrence was constructed based on a multiple logistic regression model. Discrimination and calibration were used to validate the model.

Results

Among a total of 139 patients who were finally analyzed, late recurrence occurred in 44 patients, with a median follow-up of

SUBMITTER: Jung KS 

PROVIDER: S-EPMC4049628 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature