Risk factors for rebleeding of aneurysmal subarachnoid hemorrhage: a meta-analysis.

ABSTRACT:

Background

Rebleeding is a serious complication of aneurysmal subarachnoid hemorrhaging. To date, there are conflicting data regarding the factors contributing to rebleeding and their significance.

Methods

A systematic review of PubMed and Embase databases was conducted for studies pertaining to aneurysmal subarachnoid hemorrhage (aSAH) and rebleeding in order to assess the associated risk factors. Odds ratios (ORs) and corresponding 95% confidence intervals (CIs) were estimated from fourteen studies comprised of a total of 5693 patients that met the inclusion criteria.

Results

Higher rebleeding rates were observed < 6 h after the initial aSAH (OR  = 3.22, 95% CI  = 1.46-7.12), and were associated with high systolic blood pressure (OR  = 1.93, 95% CI  = 1.31-2.83), po

SUBMITTER: Tang C 

PROVIDER: S-EPMC4049799 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature