Gut microbiota disturbance during antibiotic therapy: a multi-omic approach.

ABSTRACT: It is known that the gastrointestinal tract (GIT) microbiota responds to different antibiotics in different ways and that while some antibiotics do not induce disturbances of the community, others drastically influence the richness, diversity, and prevalence of bacterial taxa. However, the metabolic consequences thereof, independent of the degree of the community shifts, are not clearly understood. In a recent article, we used an integrative OMICS approach to provide new insights into the metabolic shifts caused by antibiotic disturbance. The study presented here further suggests that specific bacterial lineage blooms occurring at defined stages of antibiotic intervention are mostly associated with organisms that possess improved survival and colonization mechanisms, such as those of the E

SUBMITTER: Ferrer M 

PROVIDER: S-EPMC4049940 | biostudies-literature | 2014 Jan-Feb

REPOSITORIES: biostudies-literature