Chemotherapy versus surgery for initial treatment in advanced ovarian epithelial cancer.

ABSTRACT:

Background

Epithelial ovarian cancer presents at an advanced stage in the majority of women. These women require surgery and chemotherapy for optimal treatment. Conventional treatment is to perform surgery first and then give chemotherapy. However, it is not yet clear whether there are any advantages to using chemotherapy before surgery.

Objectives

To assess whether there is an advantage to treating women with advanced epithelial ovarian cancer with chemotherapy before cytoreductive surgery (neoadjuvant chemotherapy (NACT)) compared with conventional treatment where chemotherapy follows maximal cytoreductive surgery.

Search methods

For the original review we searched, the Cochrane Central Register of Controlled Trials (CENTRAL, Issue 3, 2006), MEDLINE (Silver Platter,

SUBMITTER: Morrison J 

PROVIDER: S-EPMC4050358 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature