Ontology highlight
ABSTRACT:
SUBMITTER: Grassart A
PROVIDER: S-EPMC4050722 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
The Journal of cell biology 20140602 5
Clathrin-mediated endocytosis (CME) involves the recruitment of numerous proteins to sites on the plasma membrane with prescribed timing to mediate specific stages of the process. However, how choreographed recruitment and function of specific proteins during CME is achieved remains unclear. Using genome editing to express fluorescent fusion proteins at native levels and live-cell imaging with single-molecule sensitivity, we explored dynamin2 stoichiometry, dynamics, and functional interdependen ...[more]