Current evidences on XPC polymorphisms and gastric cancer susceptibility: a meta-analysis.

ABSTRACT:

Background

Reduced DNA repair capacities due to inherited polymorphisms may increase the susceptibility to cancers including gastric cancer. Previous studies investigating the association between Xeroderma Pigmentosum group C (XPC) gene polymorphisms and gastric cancer risk reported inconsistent results. We performed a meta-analysis to summarize the possible association.

Methods

All studies published up to January 2014 on the association between XPC polymorphisms and gastric cancer risk were identified by searching electronic databases PubMed, EMBASE, Cochrane library, and Chinese Biomedical Literature database (CBM). The association between XPC polymorphisms and gastric cancer risk was assessed by odds ratios (ORs) together with their 95% confidence intervals (CIs).

Resu

SUBMITTER: Peng Q 

PROVIDER: S-EPMC4053311 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature