Characterizing 5-methylcytosine in the mammalian epitranscriptome.

ABSTRACT: The post-transcriptional modification 5-methylcytosine (m5C) occurs in a wide range of coding and non-coding RNAs. We describe transcriptome-wide approaches to capture the global m5C RNA methylome. We also discuss the potential functions of m5C in RNA and compare them to 6-methyladenosine modifications.

SUBMITTER: Hussain S 

PROVIDER: S-EPMC4053770 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature