Characterization of chromosomal architecture in Arabidopsis by chromosome conformation capture.

ABSTRACT:

Background

The packaging of long chromatin fibers in the nucleus poses a major challenge, as it must fulfill both physical and functional requirements. Until recently, insights into the chromosomal architecture of plants were mainly provided by cytogenetic studies. Complementary to these analyses, chromosome conformation capture technologies promise to refine and improve our view on chromosomal architecture and to provide a more generalized description of nuclear organization.

Results

Employing circular chromosome conformation capture, this study describes chromosomal architecture in Arabidopsis nuclei from a genome-wide perspective. Surprisingly, the linear organization of chromosomes is reflected in the genome-wide interactome. In addition, we study the interplay of the in

SUBMITTER: Grob S 

PROVIDER: S-EPMC4053840 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature