Advanced REACH Tool: a Bayesian model for occupational exposure assessment.

ABSTRACT: This paper describes a Bayesian model for the assessment of inhalation exposures in an occupational setting; the methodology underpins a freely available web-based application for exposure assessment, the Advanced REACH Tool (ART). The ART is a higher tier exposure tool that combines disparate sources of information within a Bayesian statistical framework. The information is obtained from expert knowledge expressed in a calibrated mechanistic model of exposure assessment, data on inter- and intra-individual variability in exposures from the literature, and context-specific exposure measurements. The ART provides central estimates and credible intervals for different percentiles of the exposure distribution, for full-shift and long-term average exposures. The ART can produce exposure estima

SUBMITTER: McNally K 

PROVIDER: S-EPMC4053932 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature