Study protocol for the nutritional route in oesophageal resection trial: a single-arm feasibility trial (NUTRIENT trial).

ABSTRACT:

Introduction

The best route of feeding for patients undergoing an oesophagectomy is unclear. Concerns exist that early oral intake would increase the incidence and severity of pneumonia and anastomotic leakage. However, in studies including patients after many other types of gastrointestinal surgery and in animal experiments, early oral intake has been shown to be beneficial and enhance recovery. Therefore, we aim to determine the feasibility of early oral intake after oesophagectomy.

Methods and analysis

This study is a feasibility trial in which 50 consecutive patients will start oral intake directly following oesophagectomy. Primary outcomes will be the frequency and severity of anastomotic leakage and (aspiration) pneumonia. Clinical parameters will be registered prospec

SUBMITTER: Weijs TJ 

PROVIDER: S-EPMC4054648 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature