HIV-1 drug mutations in children from northern Tanzania.

ABSTRACT:

Objectives

In resource-limited settings, it is a challenge to get quality clinical specimens due to poor infrastructure for their collection, transportation, processing and storage. Using dried blood spots (DBS) might be an alternative to plasma for HIV-1 drug resistance testing in this setting. The objectives of this study were to determine mutations associated with antiretroviral resistance among children <18 months old born to HIV-1-infected mothers enrolled in prevention of mother-to-child transmission services in northern Tanzania.

Patients and methods

Kilimanjaro Christian Medical Center (KCMC) Clinical Laboratory is the zonal centre for early infant diagnosis using DBS in northern Tanzania. DBS were collected from January 2011 to December 2012. Mothers were kept on tr

SUBMITTER: Shao ER 

PROVIDER: S-EPMC4054989 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature