Design and preliminary recruitment results of the Cluster randomised triAl of PSA testing for Prostate cancer (CAP).

ABSTRACT:

Background

Screening for prostate cancer continues to generate controversy because of concerns about over-diagnosis and unnecessary treatment. We describe the rationale, design and recruitment of the Cluster randomised triAl of PSA testing for Prostate cancer (CAP) trial, a UK-wide cluster randomised controlled trial investigating the effectiveness and cost-effectiveness of prostate-specific antigen (PSA) testing.

Methods

Seven hundred and eighty-five general practitioner (GP) practices in England and Wales were randomised to a population-based PSA testing or standard care and then approached for consent to participate. In the intervention arm, men aged 50-69 years were invited to undergo PSA testing, and those diagnosed with localised prostate cancer were invited into a tre

SUBMITTER: Turner EL 

PROVIDER: S-EPMC4056057 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature