Low-dose CT for quantitative analysis in acute respiratory distress syndrome.

ABSTRACT:

Introduction

The clinical use of serial quantitative computed tomography (CT) to characterize lung disease and guide the optimization of mechanical ventilation in patients with acute respiratory distress syndrome (ARDS) is limited by the risk of cumulative radiation exposure and by the difficulties and risks related to transferring patients to the CT room. We evaluated the effects of tube current-time product (mAs) variations on quantitative results in healthy lungs and in experimental ARDS in order to support the use of low-dose CT for quantitative analysis.

Methods

In 14 sheep chest CT was performed at baseline and after the induction of ARDS via intravenous oleic acid injection. For each CT session, two consecutive scans were obtained applying two different mAs: 60 mAs wa

SUBMITTER: Vecchi V 

PROVIDER: S-EPMC4057189 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature