The effect of glutamine therapy on outcomes in critically ill patients: a meta-analysis of randomized controlled trials.

ABSTRACT:

Introduction

Glutamine supplementation is supposed to reduce mortality and nosocomial infections in critically ill patients. However, the recently published reducing deaths due to oxidative stress (REDOX) trials did not provide evidence supporting this. This study investigated the impact of glutamine-supplemented nutrition on the outcomes of critically ill patients using a meta-analysis.

Methods

We searched for and gathered data from the Cochrane Central Register of Controlled Trials, MEDLINE, Elsevier, Web of Science and ClinicalTrials.gov databases reporting the effects of glutamine supplementation on outcomes in critically ill patients. We produced subgroup analyses of the trials according to specific patient populations, modes of nutrition and glutamine dosages.

Resul

SUBMITTER: Chen QH 

PROVIDER: S-EPMC4057299 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature