Modeling optimal cervical cancer prevention strategies in Nigeria.

ABSTRACT:

Background

This study aims to assess the most efficient combinations of vaccination and screening coverage for the prevention of cervical cancer (CC) at different levels of expenditure in Nigeria.

Methods

An optimization procedure, using a linear programming approach and requiring the use of two models (an evaluation and an optimization model), was developed. The evaluation model, a Markov model, estimated the annual number of CC cases at steady state in a population of 100,000 women for four alternative strategies: screening only; vaccination only; screening and vaccination; and no prevention. The results of the Markov model for each scenario were used as inputs to the optimization model determining the optimal proportion of the population to receive screening and/or vaccin

SUBMITTER: Demarteau N 

PROVIDER: S-EPMC4057561 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature